Piet Gros Lab

Cryo-EM structure of CD9 in complex with EWI-F; implications for Tetraspanin-enriched microdomain formation .

Structural and biochemical studies of STEAP1 suggest a role as modulator of iron(III) reduction.

Complement enhancement by oligomeric properdin explained by crystal structures of properdin and properdin/C3b-CTC complexes.

Structures of IgM-C1-C4b complexes on liposomes revealed by cryo-EM tomography.

Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction.

C1 binds heterogeneously to IgG1-Fc hexamer complexes.

Ternary complex C3b-FH-FI reveals molecular mechanisms underlying co-factor activity and complement-immune processing

Heterogeneous MAC initiator and pore structures in a lipid bilayer by phase-plate cryo-electron tomography.

Regulators of complement activity mediate inhibitory mechanisms through common C3b-binding mode

Complement is activated by IgG hexamers assembled at the cell surface.

Stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5

Structures of Wnt-antagonist ZNRF3 and its complex with stem cell growth factor R-spondin 1; implications for signaling

Modelling dynamics in protein crystal structures by ensemble refinement.